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TSQ

CAT: 0804-HY-119287-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-119287-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm) . TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence (Ex/Em = 334/495 nm) [1].
CAS Number
109628-27-5
Product Name Alternative
Fer-1
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tsq.html
Concentration
10mM
Purity
99.50
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=S(C1=CC=C(C)C=C1)(NC2=C3N=CC=CC3=CC(OC)=C2)=O
Molecular Formula
C17H16N2O3S
Molecular Weight
328.39
References & Citations
[1]Meeusen JW, et al. TSQ (6-methoxy-8-p-toluenesulfonamido-quinoline), a common fluorescent sensor for cellular zinc, images zinc proteins. Inorg Chem. 2011 Aug 15;50 (16) :7563-73.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Chemical Information

N-(6-Methoxy-8-quinolinyl)-4-methylbenzenesulfonamide
CAS Number109628-27-5
PubChem CID130606
IUPAC NameN-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide
Molecular FormulaC17H16N2O3S
Molecular Weight328.4
XLogP3
Topological Polar Surface Area76.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity483
SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=CC(=C2)OC)C=CC=N3
InChI
InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3
InChIKey
HKRNYOZJJMFDBV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(6-Methoxy-8-quinolinyl)-4-methylbenzenesulfonamide
CAS: 109628-27-5
CID: 130606
Formula: C17H16N2O3S
MW: 328.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight328.4
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass328.08816355
Monoisotopic Mass328.08816355
Topological Polar Surface Area76.7 Ų
Heavy Atom Count23
Formal Charge0
Complexity483
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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