NFKB2 Polyclonal Antibody

• Background :

  This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) . The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

• Synonyms :

  CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52

• Gene ID :

  4791

• Swiss Prot :

  Q00653

• Cellular Locus :

  Cytoplasm, Nucleus

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Target :

  NFKB2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NFKB2 (NP_002493.3) .

• Applications :

  WB, IHC, IF

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), IHC (), IF ()

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Store at -20°C for 12 months.

• Gene ID URL :

  4791