LDHB Polyclonal Antibody

• Background :

  This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

• Synonyms :

  LDHB; HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5

• Gene ID :

  3945

• Swiss Prot :

  P07195

• Cellular Locus :

  Cytoplasm

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Target :

  LDHB

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1) .

• Applications :

  WB, IHC

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), IHC ()

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Store at -20°C for 12 months.

• Gene ID URL :

  3945