EDN1 Polyclonal Antibody

• Background:

  This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

• Synonyms:

  EDN1; ARCND3; ET1; HDLCQ7; PPET1; QME; endothelin-1

• Gene ID:

  1906

• Swiss Prot:

  P05305

• Cellular Locus:

  Secreted

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  EDN1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  Recombinant fusion protein containing a sequence corresponding to amino acids 18-212 of human EDN1 (NP_001946.3) .

• Applications:

  WB, IHC, IF

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), IHC (), IF ()

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  1906