CAPN2 Polyclonal Antibody

• Background:

  The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  CAPN2; CANP2; CANPL2; CANPml; mCANP; calpain 2

• Gene ID:

  824

• Swiss Prot:

  P17655

• Cellular Locus:

  Cytoplasm, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse

• Target:

  CAPN2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  Recombinant fusion protein containing a sequence corresponding to amino acids 350-680 of human CAPN2 (NP_001739.2) .

• Applications:

  WB, IHC-P, IF (ICC), IF

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IF ()

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  824