Phospho-EIF4B (Ser504) Polyclonal Antibody

• Background :

  EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F (referenced from swissprot) .

• Synonyms :

  E 4B; E-4B; Eukaryotic initiation factor 4B; 4B_HUMAN.

• Gene ID :

  1975

• Modification Site :

  Ser504

• Cellular Locus :

  Cytoplasm

• Host :

  Rabbit

• Target :

  Phospho-EIF4B (Ser504)

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic phosphopeptide derived from human EIF4B around the phosphorylation site of Ser504

• Applications :

  WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Phosphorylation

• Storage Conditions :

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  1975

• Predicted Cross Reactivity :

  Human, Dog, Cow, Horse, Rabbit