MeCP2 Polyclonal Antibody

• Background :

  Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) -containing DNA, with a preference for 5-methylcytosine (5mC) .

• Synonyms :

  Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein

• Gene ID :

  4204

• Swiss Prot :

  P51608

• Host :

  Rabbit

• Cross Reactivity :

  Human

• Target :

  MeCP2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

• Applications :

  WB, ELISA, dot-blot

• Purification :

  Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

• Concentration :

  1.2µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), dot-blot ()

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Store at -20°C for 12 months.

• Gene ID URL :

  4204