WDR5 Polyclonal Antibody

• Background:

  Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

• Synonyms:

  WD repeat-containing protein 5, WDR5, BMP2-induced 3-kb gene protein, BIG3

• Gene ID:

  11091

• Swiss Prot:

  P61964

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  WDR5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  Polyclonal antibody raised in rabbit against human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein

• Applications:

  WB, IF, ChIP-seq

• Purification:

  Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300

• Concentration:

  2µg/µl

• Dilution:

  WB (1:300-5000), IF (), ChIP-seq ()

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  11091