PAPD5 Polyclonal Antibody

• Background:

  Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro) . Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

• Synonyms:

  Non-canonical poly (A) RNA polymerase PAPD5, PAPD5, TRF4-2, TUTase 3, PAP-associated domain-containing protein 5

• Gene ID:

  64282

• Swiss Prot:

  Q8NDF8

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  PAPD5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  Polyclonal antibody raised in rabbit against human PAPD5 (PAP associated domain containing 5), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

• Applications:

  WB, ELISA

• Purification:

  Whole antiserum from rabbit containing 0.05% azide

• Concentration:

  Not Determined

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  64282