BMI1 Polyclonal Antibody

• Background:

  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

• Synonyms:

  PCGF4, RNF51, FLVI2

• Gene ID:

  648

• Swiss Prot:

  P35226

• Host:

  Rabbit

• Cross Reactivity:

  Mouse

• Target:

  BMI1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  Polyclonal antibody raised in rabbit against mouse BMI1 using two KLH-conjugated synthetic peptides containing a sequence from the central and the C-terminal region of the protein, respectively

• Applications:

  ELISA

• Purification:

  Whole antiserum from rabbit containing 0.05% azide

• Concentration:

  Not Determined

• Dilution:

  ELISA (1:500-1000)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C for 12 months.

• Gene ID URL:

  648