SETBP1 Polyclonal Antibody

CAT: 0498-bs-4944RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-4944RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SETBP1 (SET binding protein 1), also known as SEB, is a 1,542 amino acid nuclear protein that contains three AT hook DNA-binding domains, one SKI homology region and a C-terminal SET-binding domain, which is followed by three PPLPPPPP repeats. SETBP1 may be involved in SET-related tumorigenesis and leukemogenesis by regulating the transforming activity of SKI in the nucleus or suppressing SET function. As a widely expressed protein, SETBP1 is encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
Synonyms
SEB; MRD29; SET-binding protein; SETBP1; KIAA0437
Gene ID
26040
Swiss Prot
Q9Y6X0
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
501-600/1596
Target
SETBP1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human SETBP1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
26040
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

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