CD44v3 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

• Synonyms :

  CD44 antigen; CD44 molecule; CD44v3; Heparan sulfate proteoglycan; IN; MUTCH 1; Phagocytic glycoprotein I.

• Gene ID :

  960

• Swiss Prot :

  P16070

• Host :

  Rabbit

• Cross Reactivity :

  Human

• Immunogen :

  161-260/493

• Target :

  CD44v3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human MUTCH 1

• Applications :

  FCM, IHC-P, IHC-F, IF (ICC), IF

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (ICC) (1:50-200), IF ()

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Store at -20°C for 12 months.

• Gene ID URL :

  960