LARG Polyclonal Antibody

• Background :

  Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia (from EntrezGene) . LARG has also been implicated in linking heterotrimeric G proteins to microtubule organisation in regulation of cell polarity.

• Synonyms :

  ARHGEF12; KIAA0382; leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; PRO2792; Rho guanine exchange factor GEF 12; Rho guanine nucleotide exchange factor GEF 12; Rho guanine nucleotide exchange factor 12; Similar to Mouse Lsc oncogene; ARHGC_HUMAN.

• Gene ID :

  23365

• Cellular Locus :

  Cytoplasm, Cell membrane

• Host :

  Rabbit

• Immunogen :

  515-615/1544

• Target :

  LARG

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human LARG

• Applications :

  WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  23365

• Predicted Cross Reactivity :

  Human, Mouse, Rat, Dog, Cow, Pig, Rabbit