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CACNB2 Polyclonal Antibody

CAT: 0498-bs-2996RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-2996RSize:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CACNB2 is a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily, expressed in the CNS. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. It was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.
Synonyms
Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Beta; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; calcium channel beta 2c subunit; calcium channel L-type beta 2 subunit; CACB2_HUMAN.
Gene ID
783
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
551-655/655
Target
CACNB2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CACNB2
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
783
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Horse, Chicken, Rabbit

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