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ARHG7 Polyclonal Antibody

CAT: 0498-bs-2936RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-2936RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ARHGEF7 is a p21-activated protein kinase (Pak) -interacting exchange factor that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. It is expressed ubiquitously in all the tissue examined and other isoforms are expressed mainly in the central nervous system. Regulated phosphorylation of ARHGEF7 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined.
Synonyms
ARHG7_HUMAN; ARHG7; ARHGEF 7; ARHGEF7; Beta pix; betaPix; betaPix-b; betaPix-c; Cool; COOL1; P50 antibody P50BP; P85; P85COOL1; P85SPR; PAK interacting exchange factor beta; PAK3; Pak3bp; PAK3BP; PIX; PIXB; Rho guanine nucleotide exchange factor GEF 7; Rho guanine nucleotide exchange factor GEF 7b; Rho guanine nucleotide exchange factor GEF7; Rho guanine nucleotide exchange factor 7; SH3 domain containing proline rich protein; Nbla10314; KIAA0142.
Gene ID
8874
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
201-300/803
Target
ARHG7
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ARHG7.
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8874
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit