HDAC1 Polyclonal Antibody

CAT: 0498-bs-2895RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-2895RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs) . Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1) . Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases.
Synonyms
HD 1; HD1; HDAC 1; hdac1: histone deacetylase 1; Histone deacetylase 1 HD1; Histone deacetylase 1; RPD3 reduced potassium dependency yeast homolog like 1; RPD3 reduced potassium dependency; RPD3; RPD3L1; DKFZp686H12203; GON 10. HDAC1_HUMAN
Gene ID
3065
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
HDAC1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human HDAC1
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3065
Predicted Cross Reactivity
Human, Dog, Cow, Sheep, Pig, GuineaPig

Related Products

CatalogName
bs-5388RPhospho-HDAC1 (Ser423+Ser421) Polyclonal Antibody
bsm-52080R-01HDAC1 Recombinant Antibody
bsm-52080R-TRHDAC1 Recombinant Antibody
bsm-51227MHDAC1 (1C1) Monoclonal Antibody
bsm-52080R-APC-01HDAC1 Recombinant Antibody, APC Conjugated
bsm-52080R-Cy3-01HDAC1 Recombinant Antibody, Cy3 Conjugated
bsm-52080R-HRP-01HDAC1 Recombinant Antibody, HRP Conjugated
bsm-52080R-Cy3-TRHDAC1 Recombinant Antibody, Cy3 Conjugated
bsm-52080R-Cy5-TRHDAC1 Recombinant Antibody, Cy5 Conjugated
bsm-52080R-Biotin-TRHDAC1 Recombinant Antibody, Biotin Conjugated

Alternative Products

CatalogName
MBS8592291-01HDAC1 Polyclonal Antibody
APR00145GPolyclonal HDAC1 Antibody
BZ16560HDAC1 polyclonal antibody

Popular Products