Azido-PEG11-amine

• Description:

  Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG11-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/azido-peg11-amine.html

• Purity:

  98.0

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

• Molecular Formula:

  C24H50N4O11

• Molecular Weight:

  570.67

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  1800414-71-4