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ACBI1

CAT: 0957-S9612-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S9612-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis.
CAS Number
2375564-55-7
Target
PROTAC
Activity
Others
Molecular Formula
C49H58FN9O7S
Storage Conditions
3 years -20°C powder

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