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SR18662

CAT: 0957-S8900-02Size: 10 mm/ 1 mLDry Ice: NoHazardous: No
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CAT#:0957-S8900-02Size:10 mm/ 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.
CAS Number
2505001-62-5
Target
KLF
Activity
MAPK
Molecular Formula
C16H19Cl2N3O4S
Storage Conditions
3 years -20°C powder

Chemical Information

(E)-3-(3,4-Dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide
CAS Number2505001-62-5
PubChem CID146674222
IUPAC Name(E)-3-(3,4-dichlorophenyl)-N-[2-(4-methylsulfonylpiperazin-1-yl)-2-oxoethyl]prop-2-enamide
Molecular FormulaC16H19Cl2N3O4S
Molecular Weight420.3
XLogP1.5
Topological Polar Surface Area95.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity642
SMILES
CS(=O)(=O)N1CCN(CC1)C(=O)CNC(=O)/C=C/C2=CC(=C(C=C2)Cl)Cl
InChI
InChI=1S/C16H19Cl2N3O4S/c1-26(24,25)21-8-6-20(7-9-21)16(23)11-19-15(22)5-3-12-2-4-13(17)14(18)10-12/h2-5,10H,6-9,11H2,1H3,(H,19,22)/b5-3+
InChIKey
WUJBXFXHDUVSFM-HWKANZROSA-N
Chemical Structure
2D Structure
2D structure of (E)-3-(3,4-Dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide
CAS: 2505001-62-5
CID: 146674222
Formula: C16H19Cl2N3O4S
MW: 420.3
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight420.3
XLogP31.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass419.0473327
Monoisotopic Mass419.0473327
Topological Polar Surface Area95.2 Ų
Heavy Atom Count26
Formal Charge0
Complexity642
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C13764-01SR18662
A22268-50SR18662 50mg
A22268-25SR18662 25mg
A22268-5SR18662 5mg
A22268-100SR18662 100mg
A22268-10SR18662 10mg

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