GABA Polyclonal Antibody

• Background:

  Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the brain and spinal cord. Inhibition is provoked by GABA binding resulting in hyperpolarization of the synaptic transmembrane potential of the affected neuron. GABA binding causes ion channels to open allowing either the flow of chloride or potassium ions into or out of the cell.

• Synonyms:

  Gamma-aminobutyric acid; gamma aminobutyric acid; 4 aminobutanoic acid; GABA; Gamma amino butyric acid.

• Cellular Locus:

  Cytoplasm, Secreted, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Rat, Others

• Target:

  GABA

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated GABA

• Applications:

  ELISA, IHC-P, IHC-F, IF (IHC-P)

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Cross Reactivity Details:

  GABA