PTC-028

CAT: 0957-S8662-03Size: 25 mgDry Ice: YesHazardous: No

1 / 1

CAT#:0957-S8662-03Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification.

CAS Number

1782970-28-8

Target

BMI-1

Activity

Cell Cycle

Molecular Formula

C19H12F5N5

Storage Conditions

2 years -80 in solvent

Chemical Information

6-(5,6-Difluoro-2-methyl-1H-benzimidazol-1-yl)-N-(4-(trifluoromethyl)phenyl)-2-pyrazinamine

CAS Number	1782970-28-8
PubChem CID	73427235
IUPAC Name	6-(5,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
Molecular Formula	C19H12F5N5
Molecular Weight	405.3
XLogP	4.7
Topological Polar Surface Area	55.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Heavy Atom Count	29
Formal Charge	0
Complexity	556

SMILES

CC1=NC2=CC(=C(C=C2N1C3=NC(=CN=C3)NC4=CC=C(C=C4)C(F)(F)F)F)F

InChI

InChI=1S/C19H12F5N5/c1-10-26-15-6-13(20)14(21)7-16(15)29(10)18-9-25-8-17(28-18)27-12-4-2-11(3-5-12)19(22,23)24/h2-9H,1H3,(H,27,28)

InChIKey

JEZGPBWIZWPDHP-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1782970-28-8

CID: 73427235

Formula: C19H12F5N5

MW: 405.3

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	405.3
XLogP3	4.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	405.10128621
Monoisotopic Mass	405.10128621
Topological Polar Surface Area	55.6 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	556
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes