CNTF Receptor alpha Polyclonal Antibody

• Background :

  This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011].

• Synonyms :

  CNTFR Alpha; Ciliary neurotrophic factor receptor alpha; CNTFR Alpha; CNTFR; Ciliary neurotrophic factor receptor alpha; Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR Alpha; CNTFR; CNTFR-alpha; CNTFR.

• Gene ID :

  1271

• Swiss Prot :

  P26992

• Cellular Locus :

  Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Mouse

• Immunogen :

  71-170/372

• Target :

  CNTF Receptor alpha

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human CNTF Receptor alpha

• Applications :

  WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  1271

• Predicted Cross Reactivity :

  Human, Rat, Dog