Complement C3d fragment Polyclonal Antibody, PE Conjugated

• Background:

  The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

• Synonyms:

  Acylation stimulating protein; ASP; C3; C3a anaphylatoxin; Complement C3 alpha chain; Complement C3; Complement C3 precursor; Complement component 3; Complement component C3; Complement factor 3; Plp; Complement C3d fragment; CO3_HUMAN.

• Gene ID:

  P01024

• Swiss Prot:

  718

• Host:

  Rabbit

• Cross Reactivity:

  Mouse

• Immunogen:

  991-1090/1663

• Target:

  Complement C3d fragment

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  PE

• Source:

  KLH conjugated synthetic peptide derived from human Complement C3d fragment

• Applications:

  WB

• Purification:

  Purified by Protein A.

• Excitation Emission:

  496,564nm/578nm

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  P01024

• Predicted Cross Reactivity:

  Human, Rat, Sheep, Pig