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Ataluren (PTC124)

CAT: 0957-S6003-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S6003-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation) . Phase 3.
CAS Number
775304-57-9
Target
CFTR
Activity
Transmembrane Transporters
Molecular Formula
C15H9FN2O3
Storage Conditions
2 years -80 in solvent

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