Products for Research Use Only
RegisterLogin

Metformin

CAT: 0957-S5958-03Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-S5958-03Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.
CAS Number
657-24-9
Synonyms
1,1-Dimethylbiguanide
Target
AMPK
Activity
PI3K/Akt/mTOR
Molecular Formula
C4H11N5
Storage Conditions
3 years -20°C powder

Chemical Information

Metformin

Metformin is a member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. It has a role as a geroprotector, a hypoglycemic agent, a xenobiotic and an environmental contaminant. It is functionally related to a biguanide. It is a conjugate base of a metformin(1+).

CAS Number657-24-9
PubChem CID4091
IUPAC Name3-(diaminomethylidene)-1,1-dimethylguanidine
Molecular FormulaC4H11N5
Molecular Weight129.16
XLogP-1.3
Topological Polar Surface Area91.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Heavy Atom Count9
Formal Charge0
Complexity132
SMILES
CN(C)C(=N)N=C(N)N
InChI
InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChIKey
XZWYZXLIPXDOLR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Metformin
CAS: 657-24-9
CID: 4091
Formula: C4H11N5
MW: 129.16
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight129.16
XLogP3-1.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass129.10144537
Monoisotopic Mass129.10144537
Topological Polar Surface Area91.5 Ų
Heavy Atom Count9
Formal Charge0
Complexity132
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
EK1551Mouse Meteorin/METRN ELISA Kit PicoKine®
EK1550Mouse Meteorin-like/METRNL ELISA Kit PicoKine®

Alternative Products

CatalogName
A4723-50Metformin
B1970-10000Metformin HCl
M087-1GMetformin hydrochloride

Popular Products