Recombinant MAP3K5 (660-978) Protein

• Description:

  Recombinant MAP3K5 (660-978) Protein_x000D_ Catalog number: B2017617_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 µg_x000D_ Molecular Weight or Concentration: 36.8 kDa_x000D_ Supplied as: SOLUTION_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, ASK-1, ASK1, MAPKKK5, MEKK5_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Wang W, Guo Z, Yang S, Wang H, Ding W. Upregulation of miR-199 attenuates TNF-α-induced Human nucleus pulposus cell apoptosis by downregulating MAP3K5 Biochem Biophys Res Commun. 2018 Nov 2;505(3):917-924._x000D_ 2: Chen X, Ma W, Yao Y, Zhang Q, Li J, Wu X, Mei C, Jiang X, Chen Y, Wang G, Wang K, Liu Y, Guo Y, Liu Z, Yuan Y. Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways Cell Death Dis. 2021 Apr 30;12(5):425._x000D_ 3: Kylarova S, Kosek D, Petrvalska O, Psenakova K, Man P, Vecer J, Herman P, Obsilova V, Obsil T. Cysteine residues mediate high-affinity binding of thioredoxin to ASK1 FEBS J. 2016 Oct;283(20):3821-3838._x000D_ 4: Kekulandara DN, Nagi S, Seo H, Chow CS, Ahn YH. Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling Biochemistry. 2018 Feb 6;57(5):772-780._x000D_ 5: Pleinis JM, Davis CW, Cantrell CB, Qiu DY, Zhan X. Purification, auto-activation and kinetic characterization of apoptosis signal-regulating kinase I Protein Expr Purif. 2017 Apr;132:34-43._x000D_ 6: Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade J Biol Chem. 2015 Jan 2;290(1):56-64._x000D_ 7: Yu Y, Wu D, Li Y, Qiao H, Shan Z. Ketamine enhances autophagy and endoplasmic reticulum stress in rats and SV-HUC-1 cells via activating IRE1-TRAF2-ASK1-JNK pathway Cell Cycle. 2021 Sep;20(18):1907-1922._x000D_ 8: Lee KI, Choi HG, Son YJ, Whang J, Kim K, Jeon HS, Park HS, Back YW, Choi S, Kim SW, Choi CH, Kim HJ. Mycobacterium avium MAV2052 protein induces apoptosis in murine macrophage cells through Toll-like receptor 4 Apoptosis. 2016 Apr;21(4):459-72._x000D_ 9: Volynets GP, Gorbatiuk OB, Kukharenko OP, Usenko MO, Yarmoluk SM. Production of recombinant human apoptosis signal-regulating kinase 1 (ASK1) in Escherichia coli Protein Expr Purif. 2016 Oct;126:89-92._x000D_ 10: Lin CL, Ying TH, Yang SF, Chiou HL, Chen YS, Kao SH, Hsieh YH. MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis Cell Death Dis. 2021 May 6;12(5):451. _x000D_ _x000D_ Products Related to Recombinant MAP3K5 (660-978) Protein can be found at Proteins

• Short Description:

  Catalog Number: B2017617 (10 µg)_x000D_ Recombinant MAP3K5 (660-978) Protein is a fragment of the MAP3K5 protein. MAP3K5, or apoptosis signal-regulating kinase 1 (ASK1), regulates cell death and survival pathways. This recombinant protein aids in studying protein function and interactions in cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3