Methamphetamine Polyclonal Antibody

CAT: 0498-bs-2076RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-2076RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH) . METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
Synonyms
D-Desoxyephedrine hydrochloride; d-N; -Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride.
Host
Rabbit
Cross Reactivity
Others
Target
Methamphetamine
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated to Methamphetamine
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Cross Reactivity Details
Methamphetamine

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