CREB-1 Polyclonal Antibody

• Background:

  Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

• Synonyms:

  Low-density lipoprotein receptor precursor; LDL-R; LDL R; FH; FHC; LDL R; LDLR; Low Density Lipoprotein Receptor; Low density lipoprotein receptor familial hypercholesterolemia.

• Gene ID:

  3949

• Swiss Prot:

  P16220

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Immunogen:

  51-120/341

• Target:

  CREB-1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human CREB-1

• Applications:

  WB, ELISA, FCM

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  3949