RAB11-FIP2 Polyclonal Antibody

• Background:

  A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

• Synonyms:

  RAB11FIP2; KIAA0941; NRip11; RAB11 family interacting protein 2 (class I) ; Rab11 family-interacting protein 2; RAB11 FIP2 long isoform; Rab11-FIP2; RFIP2; RFIP2_HUMAN.

• Gene ID:

  22841

• Swiss Prot:

  Q7L804

• Cellular Locus:

  Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse

• Immunogen:

  331-430/512

• Target:

  RAB11-FIP2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human RAB11-FIP2

• Applications:

  WB, ELISA

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  22841

• Predicted Cross Reactivity:

  Rat, Dog, Cow, Pig, Horse, Chicken, Cat, Rabbit, GuineaPig