Products for Research Use Only
RegisterLogin

PTPN12 Polyclonal Antibody

CAT: 0498-bs-19589RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-19589RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Synonyms
Protein tyrosine phosphatase G1; Protein tyrosine phosphatase non receptor type 12; Protein-tyrosine phosphatase G1; PTN12_HUMAN; PTP PEST; PTP-PEST; PTPG1; Ptpn12; Tyrosine protein phosphatase non receptor type 12; Tyrosine-protein phosphatase non-receptor type 12.
Gene ID
5782
Swiss Prot
Q05209
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
1-100/780
Target
PTPN12
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PTPN12
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5782
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Related Products

CatalogName
bsm-60705R-01PTPN12 Recombinant Antibody
bsm-60705R-TRPTPN12 Recombinant Antibody
bs-101804P-01Recombinant Human PTPN12 Protein, N-His
bs-55183RPTPN11 Polyclonal Antibody
bs-25352RPTPN11 Polyclonal Antibody
bs-5760RPTPN13 Polyclonal Antibody
bs-55182RPTPN1 Polyclonal Antibody
bs-0182RPTPN1 Polyclonal Antibody
bs-0644RPTP4A2 Polyclonal Antibody
bs-9187RPTPH1 Polyclonal Antibody

Alternative Products

CatalogName
MBS2530317-01PTPN12 Polyclonal Antibody
BS78072PTPN12 polyclonal antibody
NB100-60666Rabbit Polyclonal PTPN12 Antibody
TA357307Ptpn12 Rabbit Polyclonal Antibody
TMAB-11925-01Anti-PTPN12 Polyclonal Antibody

Popular Products