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Ginsenoside Rd

CAT: 0957-S3931Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S3931Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
CAS Number
52705-93-8
Synonyms
Panaxoside Rd, Sanchinoside Rd
Target
COX
Activity
Neuronal Signaling
Molecular Formula
C48H82O18
Storage Conditions
2 years -80 in solvent

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