Products for Research Use Only
RegisterLogin

Phospho-MCL1 (Ser159) Polyclonal Antibody

CAT: 0498-bs-18726RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-18726RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.
Synonyms
MCL1 (phospho S159) ; p-MCL1 (phospho S159) ; Bcl 2 related protein EAT/mcl1; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; BCL2 related; Bcl2-L-3; BCL2L3; EAT; Induced myeloid leukemia cell differentiation protein Mcl 1; Induced myeloid leukemia cell differentiation protein Mcl-1; MCL 1; MCL1; MCL1-ES; Mcl1/EAT; MCL1_HUMAN; MCL1L; MCL1S; MGC104264; MGC1839; Myeloid Cell Leukemia 1; Myeloid cell leukemia ES; Myeloid cell leukemia sequence 1; Myeloid cell leukemia sequence 1 BCL2 related; Myeloid cell leukemia sequence 1 isoform 1; OTTHUMP00000032794; OTTHUMP00000032795; TM.
Gene ID
4170
Swiss Prot
Q07820
Modification Site
Ser159
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-MCL1 (Ser159)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthesised phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159.
Applications
IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4170

Related Products

CatalogName
bs-3265R-01Phospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody
bs-3265R-TRPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody
bs-3265R-PEPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, PE Conjugated
bs-3265R-BiotinPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, Biotin Conjugated
bs-3265R-PerCPPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, PerCP Conjugated
bs-3265R-Cy5Phospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, Cy5 Conjugated
bs-3265R-RBITCPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, RBITC Conjugated
bs-3265R-HRPPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, HRP Conjugated
bs-3265R-FITCPhospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, FITC Conjugated
bs-3265R-Cy7Phospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, Cy7 Conjugated

Alternative Products

CatalogName
BS65107-01MCL1 (Phospho-Ser159) polyclonal antibody
AF3613-01Phospho-MCL1 (Ser159) Antibody
A1981-100Phospho MCL1 (Ser159) Antibody
MBS858682-01MCL1 (Phospho-Ser159) Antibody
OASG04407-100ULMCL1 Antibody (Phospho-Ser159)
TMAB-10957-01Anti-Phospho-MCL1 (Ser159) Polyclonal Antibody
GTR17707428-01Phospho-MCL1 (Ser159) Rabbit Polyclonal Antibody
GTR17847913Phospho-MCL1 (Ser159) Rabbit Polyclonal Antibody (RBITC)
GTR17847735Phospho-MCL1 (Ser159) Rabbit Polyclonal Antibody (Cy7)
GTR17804526Phospho-MCL1 (Ser159) Rabbit Polyclonal Antibody (Cy3)

Popular Products