Products for Research Use Only
RegisterLogin

Agrimol B

CAT: 0804-HY-N0704-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0704-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator. Agrimol B shows anti-adipogenic and anticancer activity. Agrimol B shows antibacterial activity against plant pathogens. Agrimol B dramatically inhibits 3T3-L1 adipocyte differentiation by reducing PPARγ, C/EBPα, FAS, UCP-1, and apoE expression. The action of Agrimol B on the cancer cells is likely derived from its effect on c-MYC, SKP2 and p27[1][2][3].
CAS Number
55576-66-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; c-Myc; Fatty Acid Synthase (FASN) ; PPAR; Sirtuin
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/agrimol-b.html
Purity
99.75
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC[C@H](C)C(C1=C(O)C(CC2=C(O)C(C(CCC)=O)=C(OC)C(C)=C2O)=C(O)C(CC3=C(O)C(C(CCC)=O)=C(OC)C(C)=C3O)=C1O)=O
Molecular Formula
C37H46O12
Molecular Weight
682.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Agrimol B, et al. Agrimol B suppresses adipogenesis through modulation of SIRT1-PPAR gamma signal pathway. Biochem Biophys Res Commun. 2016 Aug 26;477 (3) :454-60.|[2]Hnit SST, et al. Agrimol B present in Agrimonia pilosa Ledeb impedes cell cycle progression of cancer cells through G0 state arrest. Biomed Pharmacother. 2021 Sep;141:111795. |[3]Chun S B, et al. Antibacterial Activities against Plant Pathogens and Identification of Agrimol B from Agrimonia pilosa LEDEB[J]. 농약과학회지 제10권 3호, 2006, 10 (3) :230-236.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARγ; SIRT1

Related Products

CatalogName
HY-N16491Agrimol C
HY-W777997Nocardicin B
HY-W713570-01Nectandrin B
HY-W777995-01Clindamycin B
HY-W013935-01Bisphenol B
HY-N8507Tunicamycin B
HY-N7046-01Silybin B
HY-162836-01Rifamycin B
HY-N7637-01Tubuloside B
HY-N0800-01Protosappanin B

Alternative Products

CatalogName
T4S1173-01Agrimol B
TBZ2438Agrimol D
TBZ30071Agrimol C
TBZ30072Agrimol F
TBZ30073Agrimol G
A14715-50Agrimol B 50mg
A14715-25Agrimol B 25mg
A14715-100Agrimol B 100mg
A14715-10Agrimol B 10mg
A14715-5Agrimol B 5mg

Popular Products