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Cyclosporin A

CAT: 0957-S2286-01Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S2286-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclosporin A, a non-polar cyclic oligopeptide, is an immunosuppressive agent that binds to cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay. Cyclosporin A is generally given following transplant surgery to prevent rejection and has been used to test its toxic effect on a perfused 3D proximal tubule model.Cyclosporin A (NSC 290193) can be used to induce animal models of Chronic Rejection of Liver Transplantation.
CAS Number
59865-13-3
Synonyms
Cyclosporine A, Cyclosporine, Ciclosporin, CsA, NSC 290193
Target
Immunology & Inflammation related
Activity
Immunology & Inflammation
Molecular Formula
C62H111N11O12
Storage Conditions
2 years -80 in solvent