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Pomalidomide

CAT: 0957-S1567-04Size: 1 gDry Ice: YesHazardous: No
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CAT#:0957-S1567-04Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN) . Pomalidomide promotes apoptosis and cell cycle arrest.
CAS Number
19171-19-8
Synonyms
CC-4047
Target
TNF-alpha
Activity
Apoptosis
Molecular Formula
C13H11N3O4
Storage Conditions
2 years -80 in solvent

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