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Cucurbitacin IIb

CAT: 0957-S0949-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S0949-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB, blocks nuclear translocation of NF-κB and decreases mRNA levels of IκBα and TNF-α. Cucurbitacin IIb exhibits anti-inflammatory activity and induces apoptosis. Cucurbitacin IIb is isolated from Hemsleya amabilis.
CAS Number
50298-90-3
Synonyms
CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A
Target
STAT
Activity
Apoptosis
Molecular Formula
C30H48O7
Storage Conditions
3 years -20°C powder

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