β-Amyloid (1-42), human

CAT: 0957-P1003Size: 5 mgDry Ice: YesHazardous: No

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CAT#:0957-P1003Size:5 mg

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Description

β-Amyloid (1-42), human is a peptide fragment composed of 42 amino acids, derived from amyloid precursor protein (APP), and plays a crucial role in Alzheimer's disease (AD) . It self-aggregates into oligomers and fibrils, with the oligomeric form being the most neurotoxic. These aggregates form amyloid plaques, a characteristic feature of AD, which interfere with cellular functions, cause mitochondrial dysfunction, and lead to neuronal cell death through oxidative stress, calcium dysregulation, and inflammation.

CAS Number

107761-42-2

Synonyms

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

Molecular Formula

C203H311N55O60S

Storage Conditions

3 years-20°C powder 1 years-80°C in solvent

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β-Amyloid (1-42), human

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