INT11/CPSF3L Polyclonal Antibody, Cy7 Conjugated

• Background:

  Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.

• Synonyms:

  RC68; INT11; RC-68; INTS11; CPSF73L; Integrator complex subunit 11; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; CPSF3L

• Gene ID:

  54973

• Swiss Prot:

  Q5TA45

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Mouse, Rat

• Immunogen:

  151-250/600

• Target:

  INT11/CPSF3L

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Cy7

• Source:

  KLH conjugated synthetic peptide derived from human INT11

• Applications:

  WB, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Excitation Emission:

  743nm/767nm

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  54973

• Predicted Cross Reactivity:

  Human, Horse, Zebrafish, Orangutan, Rhesus monkey, Gorilla, Opossum, Elephant