HEY1 polyclonal antibody

• Background:

  This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

• Gene ID:

  23462

• Swiss Prot:

  Q9Y5J3

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Immunogen:

  51-150/304

• Target:

  HEY1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA, IHC-P, IHC-F, IF

• Purification:

  Purified by Protein A.

• Concentration:

  1mg/ml

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  23462

• Predicted Cross Reactivity:

  Human, Mouse, Rat, Dog, Cow, Sheep, Horse