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MAD1 Polyclonal Antibody

CAT: 0498-bs-1595RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-1595RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
Synonyms
Mitosis arrest deficiency 1; hMAD1; HsMAD1; MAD1L1; Mitotic arrest deficient 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; PIG9; Tax binding protein 181; TP53I9 ; Tumor protein p53 inducible protein 9; TXBP181; MD1L1_HUMAN.
Gene ID
8379
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
101-200/718
Target
MAD1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human MAD1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8379
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Horse

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