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Reelin Polyclonal Antibody

CAT: 0498-bs-1560RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-1560RSize:100 µL
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Background
Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity) .
Synonyms
RL; ETL7; LIS2; PRO1598; Reelin; RELN
Gene ID
5649
Swiss Prot
P78509
Cellular Locus
Extracellular, Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
3320-3370/3458
Target
Reelin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human RELN
Applications
IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5649

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