BPU

• Description :

  BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; MMP

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bpu.html

• Purity :

  99.04

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  O=C(N)N(C1=NC=C(Br)N=C1)CC2=CC=CC(C(F)(F)F)=C2

• Molecular Formula :

  C13H10BrF3N4O

• Molecular Weight :

  375.14

• References & Citations :

  [1]Yasser Hussein Issa Mohammed, et al. Discovery of 1- (5-bromopyrazin-2-yl) -1-[3- (trifluoromethyl) benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Sci Rep. 2023, 13, 1.|[2]Yasser Hussein Issa Mohammed, et al. Discovery of 1- (5-bromopyrazin-2-yl) -1-[3- (trifluoromethyl) benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Scientific Reports. Dec 12.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported