AP2 beta Polyclonal Antibody

• Background:

  Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

• Synonyms:

  Adaptin beta 1 beta prime; _-Adaptin; Adaptin _1; Adaptin-_1; Adaptin beta 2 beta; Adaptin beta 2; Adaptin, beta 2 beta; Adaptor protein complex AP 1 beta 1 subunit; Adaptor related protein complex 1 beta 1 subunit; Adaptor related protein complex 1, beta 1 subunit; Adaptor related protein complex 2 beta 1 subunit; Adaptor related protein complex 2, beta 1 subunit; ADTB 1; ADTB 2; ADTB1; ADTB2; AP 1 complex subunit beta 1; AP 105A; AP 105B; AP 2 complex subunit beta 1; AP1 Beta; AP1 complex subunit beta 1; AP105A; AP105B; AP1B1; AP2 beta; AP2 complex subunit beta 1; AP2B1; AP2beta; BAM 22; BAM22; Beta adaptin; Beta prime adaptin; Beta1 adaptin; Beta2 adaptin; CLAPB 1; CLAPB 2; CLAPB1; CLAPB2; Clathrin assembly protein complex 1; Clathrin assembly protein complex 1 beta large chain; Clathrin assembly protein complex 2 beta large chain; Clathrin associated/assembly/adaptor protein large beta 1; Clathrin associated/assembly/adaptor protein large beta 2; DKFZp781K0743; Golgi adaptor HA1/AP1 adaptin beta subunit; Plasma membrane adaptor HA2/AP2 adaptin beta subunit; Plasma membrane adaptor HA2/AP2 adaptor beta subunit; Plasma membrane adaptor HA2/AP2.

• Gene ID:

  2971

• Cellular Locus:

  Cytoplasm, Cell membrane

• Host:

  Rabbit

• Immunogen:

  351-450/937

• Target:

  AP2 beta

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human beta Adaptin

• Applications:

  ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  2971

• Predicted Cross Reactivity:

  Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit