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Prednicarbate

CAT: 0804-HY-B1365-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1365-01Size:5 mg
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Description
Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis[1][2].
CAS Number
73771-04-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/prednicarbate.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])[C@H](C2)O)([H])CC1)C)OC(OCC)=O)=O)=O
Molecular Formula
C27H36O8
Molecular Weight
488.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Lubach D, et, al. Investigation of the skin thinning effect of prednicarbate and other corticoids in mouse skin. Skin Pharmacol. 1988;1 (3) :200-6.|[2]Lee KH, et, al. Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice. J Pharm Pharmacol. 2014 Mar;66 (3) :466-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched