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GCM2 Polyclonal Antibody

CAT: 0498-bs-13314RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-13314RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
Synonyms
Chorion-specic transcription factor GCMb; GCM mot protein 2; GCMb; Glial cells missing homolog 2; glial cells missing homolog b; GCM2_HUMAN.
Gene ID
9247
Swiss Prot
O75603
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
61-160/506
Target
GCM2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GCM2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
9247
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Pig, Horse, Rabbit