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G gamma3 Polyclonal Antibody

CAT: 0498-bs-13244RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-13244RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the Beta subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the Gamma as well as the Alpha and Beta subunits, and that preferential associations between members of subunit families increase G protein functional diversity.
Synonyms
GBG3_HUMAN; GNG3; Guanine nucleotide-binding protein GI/GS/GO gamma-3 subunit; Guanine nucleotide-binding protein GI/GS/GO subunit gamma-3.
Gene ID
2785
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
21-55/75
Target
G gamma3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human G gamma3
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
2785
Predicted Cross Reactivity
Human, Mouse, Rat, Chicken

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