MAPK4 Polyclonal Antibody, FITC Conjugated

• Background:

  Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity) .

• Synonyms:

  ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK; Mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; MAP kinase isoform p63; MAPK4

• Gene ID:

  5596

• Swiss Prot:

  P31152

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Rat

• Immunogen:

  21-130/587

• Target:

  MAPK4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  FITC

• Source:

  KLH conjugated synthetic peptide derived from human ERK4/MAPK4

• Applications:

  IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Excitation Emission:

  494nm/518nm

• Concentration:

  1µg/µl

• Dilution:

  IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  5596

• Predicted Cross Reactivity:

  Mouse