Products for Research Use Only
RegisterLogin

FMN1 Polyclonal Antibody

CAT: 0498-bs-13185RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-13185RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.
Synonyms
FMN; Formin 1; Formin1; Formin-1; LD; Limb deformity protein homolog; FMN1_HUMAN.
Gene ID
342184
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
651-750/1419
Target
FMN1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human FMN1/Formin 1
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
342184
Predicted Cross Reactivity
Mouse, Dog, Cow, Sheep

Related Products

CatalogName
bs-42131P-01Recombinant human FMN1 protein, His
bs-6812R-01FMNL1 Polyclonal Antibody
bs-6812R-TRFMNL1 Polyclonal Antibody
bs-9957RCREG2 Polyclonal Antibody
bs-9952RC12ORF54 Polyclonal Antibody
bs-9951RC12ORF53 Polyclonal Antibody
bs-9941RC11orf71 Polyclonal Antibody
bs-9940RC11orf65 Polyclonal Antibody
bs-9939RC11orf57 Polyclonal Antibody
bs-9937RC11orf24 Polyclonal Antibody

Alternative Products

CatalogName
MBS2554853-01FMN1 Polyclonal Antibody
NBP3-35318-20ulRabbit Polyclonal FMN1 Antibody
GTR18287267FMN1 Polyclonal Conjugated Antibody
GTR17875949FMN1 Rabbit Polyclonal Antibody
TMAB-06085-01Anti-FMN1 Polyclonal Antibody
H00342184-B01PMouse Polyclonal FMN1 Antibody

Popular Products