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STZ (Streptozotocin)

CAT: 0957-S1312-01Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S1312-01Size:50 mg
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Description
STZ (Streptozotocin) is a glucosamine-nitrosourea compound derived from Streptomyces achromogenes, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. Streptozotocin induces autophagy and apoptosis. Streptozotocin (STZ) can be used to induce animal models of diabetes. Solutions are unstable and should be fresh-prepared.
CAS Number
18883-66-4
Synonyms
NSC-85998, Streptozocin, U 9889, STZ
Target
DNA alkylator
Activity
DNA Damage/DNA Repair
Molecular Formula
C8H15N3O7
Storage Conditions
2 years -80 in solvent

Chemical Information

Streptozocin

Streptozotocin (Streptozocin) can cause cancer according to an independent committee of scientific and health experts. It can cause developmental toxicity, female reproductive toxicity and male reproductive toxicity according to state or federal government labeling requirements.

CAS Number18883-66-4
PubChem CID29327
IUPAC Name1-methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
Molecular FormulaC8H15N3O7
Molecular Weight265.22
XLogP-1.4
Topological Polar Surface Area152
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Heavy Atom Count18
Formal Charge0
Complexity315
SMILES
CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
InChI
InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
InChIKey
ZSJLQEPLLKMAKR-GKHCUFPYSA-N
Chemical Structure
2D Structure
2D structure of Streptozocin
CAS: 18883-66-4
CID: 29327
Formula: C8H15N3O7
MW: 265.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight265.22
XLogP3-1.4
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass265.09099983
Monoisotopic Mass265.09099983
Topological Polar Surface Area152 Ų
Heavy Atom Count18
Formal Charge0
Complexity315
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-13753-01Streptozotocin
A10868-1000Streptozotocin 1g
A10868-500Streptozotocin 500mg
MBS8506230-01Streptozotocin (Zanosar)
GTR19288771-01Streptozocin (Streptozotocin)
S1312-50mgSTZ (Streptozotocin)

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