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POLK Polyclonal Antibody

CAT: 0498-bs-13019RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-13019RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.
Synonyms
DNA polymerase kappa; DINB protein; Short=DINP; POLK_HUMAN.
Gene ID
51426
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
1-100/870
Target
POLK
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
Applications
FCM
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
FCM (1:20-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51426

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